Arabidopsis WAT1 is a vacuolar auxin transport facilitator required for auxin homoeostasis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F13%3A33148264" target="_blank" >RIV/61989592:15310/13:33148264 - isvavai.cz</a>
Alternative codes found
RIV/61389030:_____/13:00421943
Result on the web
<a href="http://www.nature.com/ncomms/2013/131016/ncomms3625/full/ncomms3625.html" target="_blank" >http://www.nature.com/ncomms/2013/131016/ncomms3625/full/ncomms3625.html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/ncomms3625" target="_blank" >10.1038/ncomms3625</a>
Alternative languages
Result language
angličtina
Original language name
Arabidopsis WAT1 is a vacuolar auxin transport facilitator required for auxin homoeostasis
Original language description
The plant hormone auxin (indole-3-acetic acid, IAA) has a crucial role in plant development. Its spatiotemporal distribution is controlled by a combination of biosynthetic, metabolic and transport mechanisms. Four families of auxin transporters have beenidentified that mediate transport across the plasma or endoplasmic reticulum membrane. Here we report the discovery and the functional characterization of the first vacuolar auxin transporter. We demonstrate that WALLS ARE THIN1 (WAT1), a plant-specificprotein that dictates secondary cell wall thickness of wood fibres, facilitates auxin export from isolated Arabidopsis vacuoles in yeast and in Xenopus oocytes. We unambiguously identify IAA and related metabolites in isolated Arabidopsis vacuoles, suggesting a key role for the vacuole in intracellular auxin homoeostasis. Moreover, local auxin application onto wat1 mutant stems restores fibre cell wall thickness. Our study provides new insight into the complexity of auxin transport in p
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EF - Botany
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nature Communications
ISSN
2041-1723
e-ISSN
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Volume of the periodical
4
Issue of the periodical within the volume
říjen
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
2625
UT code for WoS article
000326472200014
EID of the result in the Scopus database
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