Triggering Mechanism for DNA Electrical Conductivity: Reversible Electron Transfer between DNA and Iron Oxide Nanoparticles

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33154806" target="_blank" >RIV/61989592:15310/15:33154806 - isvavai.cz</a>

Result on the web

<a href="http://onlinelibrary.wiley.com/doi/10.1002/adfm.201404372/epdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/adfm.201404372/epdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/adfm.201404372" target="_blank" >10.1002/adfm.201404372</a>

Result language

angličtina

Original language name

Triggering Mechanism for DNA Electrical Conductivity: Reversible Electron Transfer between DNA and Iron Oxide Nanoparticles

Original language description

A new category of iron oxide nanoparticles (surface active maghemite nanoparticles (SAMNs, ?-Fe2O3)) allows the intimate chemical and electrical contact with DNA by direct covalent binding. On these basis, different DNA-nanoparticle architectures are developed and used as platform for studying electrical properties of DNA. The macroscopic 3D nanobioconjugate, constituted of 5% SAMNs, 70% water, and 25% DNA, shows high stability, electrochemical reversibility and, moreover, electrical conductivity (70-80? cmMINUS SIGN 1). Reversible electron transfer at the interface between nanoparticles and DNA is unequivocally demonstrated by Mössbauer spectroscopy, which shows the appearance of Fe(II) atoms on nanoparticles following nanobioconjugate formation. This represents the first example of permanent electron exchange by DNA, as well as, of DNA conductivity at a macroscopic scale. Finally, the most probable configuration of the binding is tentatively modeled by density functional theory (DFT

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BO - Biophysics

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Advanced Functional Materials

ISSN

1616-3028

e-ISSN

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Volume of the periodical

25

Issue of the periodical within the volume

12

Country of publishing house

DE - GERMANY

Number of pages

10

Pages from-to

1822-1831

UT code for WoS article

000351683200013

EID of the result in the Scopus database

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