Magnetic Nanoparticles with Covalently Bound Self-Assembled Protein Corona for Advanced Biomedical Applications
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F13%3A33145789" target="_blank" >RIV/61989592:15310/13:33145789 - isvavai.cz</a>
Result on the web
<a href="http://pubs.acs.org/doi/ipdf/10.1021/jp4068137" target="_blank" >http://pubs.acs.org/doi/ipdf/10.1021/jp4068137</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/jp4068137" target="_blank" >10.1021/jp4068137</a>
Alternative languages
Result language
angličtina
Original language name
Magnetic Nanoparticles with Covalently Bound Self-Assembled Protein Corona for Advanced Biomedical Applications
Original language description
Novel surface active maghemite nanoparticles (SAMNs) possessing peculiar colloidal properties and surface characteristics are able to covalently bind biomolecules. The interactions of SAMNs and rhodamine derivatized SAMNs (SAMN@RITC) with proteins from cell culture medium were studied by gel electrophoresis and mass spectrometry. Among the 3000 proteins present in fetal calf serum, SAMNs. and SAMN@RITC give rise to the formation of a self-assembled corona shell with 22 selected proteins, representing minor plasma proteins, among which alpha-2-HS- glycoprotein stands. out Bovine serum albumin: (BSA), representing 80% of the total serum proteins, shows negligible absorption on the SAMN surface: Nevertheless; SAMNs :. are able to bind BSA, upon incubationin pure BSA solutions The interaction between SAMNs and BSA was investigated by optical Spectroscopy, circular dichroism, Fourier transform infrared spectroscopy, and transmission electron microscopy. BSA binding resulted a time consumin
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Physical Chemistry Part C: Nanomaterials and Interfaces
ISSN
1932-7447
e-ISSN
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Volume of the periodical
117
Issue of the periodical within the volume
39
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
20320-20331
UT code for WoS article
000326300700062
EID of the result in the Scopus database
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