Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F17%3A73580955" target="_blank" >RIV/61989592:15310/17:73580955 - isvavai.cz</a>
Result on the web
<a href="http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=15697&path%5B%5D=50198" target="_blank" >http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=15697&path%5B%5D=50198</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.18632/oncotarget.15697" target="_blank" >10.18632/oncotarget.15697</a>
Alternative languages
Result language
angličtina
Original language name
Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications
Original language description
Vitamin D receptor (VDR) is a member of the nuclear receptor (NR) superfamily of ligand-activated transcription factors. Activated VDR is responsible for maintaining calcium and phosphate homeostasis, and is required for proper cellular growth, cell differentiation and apoptosis. The expression of both phases I and II drug-metabolizing enzymes is also regulated by VDR, therefore it is clinically important. Post-translational modifications of NRs have been known as an important mechanism modulating the activity of NRs and their ability to drive the expression of target genes. The aim of this mini review is to summarize the current knowledge about post-transcriptional and post-translational modifications of VDR.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
<a href="/en/project/GBP303%2F12%2FG163" target="_blank" >GBP303/12/G163: Centre of drug-dietary supplements interactions and nutrigenetics</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Oncotarget
ISSN
1949-2553
e-ISSN
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Volume of the periodical
8
Issue of the periodical within the volume
21
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
35390-35402
UT code for WoS article
000402051700121
EID of the result in the Scopus database
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