Chapter 2 - Basis of mass spectrometry: Technical variants

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F18%3A73590208" target="_blank" >RIV/61989592:15310/18:73590208 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/B9780128144510000022" target="_blank" >https://www.sciencedirect.com/science/article/pii/B9780128144510000022</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/B978-0-12-814451-0.00002-2" target="_blank" >10.1016/B978-0-12-814451-0.00002-2</a>

Result language
angličtina
Original language name
Chapter 2 - Basis of mass spectrometry: Technical variants
Original language description
Chapter 2, Basis of Mass Spectrometry: Technical Variants, provides a definition of mass spectrometry (MS) and describes the history of this analytical technique from the very beginning. Then it summarizes basic components of a mass spectrometer, from which namely mass analyzers are further described in detail together with their combinations in hybrid mass spectrometers. Such instruments are designed to perform tandem MS, which has been used in chemistry and biology to identify and quantify compounds. All possible modes of tandem MS are mentioned as well as common ion activation techniques for the fragmentation of gas-phase ions, which is essential and occurs between different stages of mass analysis. Next, separation techniques hyphenated with MS are discussed, namely gas and liquid chromatography (GC and LC, respectively) and capillary electrophoresis (CE). Hyphenated systems are nowadays almost indispensable for investigations of complex biological samples containing proteins, lipids, or metabolites. Mass spectrometry imaging (MSI) is presented as a tool for direct analyses of biological tissues. The chapter is ended by a part devoted to data representation and management with a focus on free and open source software and data formats. The text is accompanied by a list of the cited literature.
Czech name
—
Czech description
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Project
<a href="/en/project/LO1204" target="_blank" >LO1204: Sustainable development of research in the Centre of the Region Haná</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name
The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology
ISBN
978-0-12-814451-0
Number of pages of the result
27
Pages from-to
19-45
Number of pages of the book
281
Publisher name
Elsevier Inc.
Place of publication
Philadelphia
UT code for WoS chapter
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