More precise, more universal and more specific - the next generation of RNA-guided endonucleases for genome editing

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F19%3A73598604" target="_blank" >RIV/61989592:15310/19:73598604 - isvavai.cz</a>
Result on the web
<a href="https://febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.15079" target="_blank" >https://febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.15079</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/febs.15079" target="_blank" >10.1111/febs.15079</a>

Result language
angličtina
Original language name
More precise, more universal and more specific - the next generation of RNA-guided endonucleases for genome editing
Original language description
CRISPR is a prokaryotic defence system that was adapted as a tool for genome editing and has become one of the most important discoveries of this century. CRISPR‐associated endonucleases cleave DNA at precise sites, which are marked by complementary short‐guided RNA. The recently developed versions of endonucleases are compatible with a broad range of PAM motifs, have a higher specificity and enable a specific nucleotide to be replaced.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10603 - Genetics and heredity (medical genetics to be 3)

Project
<a href="/en/project/EF16_019%2F0000827" target="_blank" >EF16_019/0000827: Plants as a tool for sustainable global development</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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