Biotechnological applications of nanostructured hybrids of polyamine carbon quantum dots and iron oxide nanoparticles
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F20%3A73601438" target="_blank" >RIV/61989592:15310/20:73601438 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/article/10.1007/s00726-019-02721-6" target="_blank" >https://link.springer.com/article/10.1007/s00726-019-02721-6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00726-019-02721-6" target="_blank" >10.1007/s00726-019-02721-6</a>
Alternative languages
Result language
angličtina
Original language name
Biotechnological applications of nanostructured hybrids of polyamine carbon quantum dots and iron oxide nanoparticles
Original language description
The combination of different nanomaterials has been investigated during the past few decades and represents an exciting challenge for the unexpected emerging properties of the resulting nano-hybrids. Spermidine (Spd), a biogenic polyamine, has emerged as a useful functional monomer for the development of carbon quantum dots (CQDs). Herein, an electrostatically stabilized ternary hybrid, constituted of iron oxide-DNA (the core) and spermidine carbon quantum dots (CQD(Spds), the shell), was self-assembled and fully characterized. The as-obtained nano-hybrid was tested on HeLa cells to evaluate its biocompatibility as well as cellular uptake. Most importantly, besides being endowed by the magnetic features of the core, it displayed drastically enhanced fluorescence properties in comparison with parent CQD(Spds) and it is efficiently internalized by HeLa cells. This novel ternary nano-hybrid with multifaceted properties, ranging from fluorescence to superparamagnetism, represents an interesting option for cell tracking.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
<a href="/en/project/LO1204" target="_blank" >LO1204: Sustainable development of research in the Centre of the Region Haná</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
AMINO ACIDS
ISSN
0939-4451
e-ISSN
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Volume of the periodical
52
Issue of the periodical within the volume
2
Country of publishing house
AT - AUSTRIA
Number of pages
11
Pages from-to
301-311
UT code for WoS article
000519385700017
EID of the result in the Scopus database
2-s2.0-85064275104