Convenient Synthesis of Furo[3,2-b]quinolin-4(1H)-ones

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F20%3A73603847" target="_blank" >RIV/61989592:15310/20:73603847 - isvavai.cz</a>

Result on the web

<a href="https://obd.upol.cz/id_publ/333183733" target="_blank" >https://obd.upol.cz/id_publ/333183733</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1055/s-0039-1691743" target="_blank" >10.1055/s-0039-1691743</a>

Result language

angličtina

Original language name

Convenient Synthesis of Furo[3,2-b]quinolin-4(1H)-ones

Original language description

In this work, we report the simple synthesis of furo[3,2-b]quinolin-4(1H)-ones from readily available 4-ethynyl-[1,3]dioxolo[4,5-c]quinolone as the key starting material. After Sonogashira (hetero)arylation, formation of the furoquinoline scaffold was accomplished using methanesulfonic acid and metal-free conditions. Although the cyclization was affected by the substitution of reaction intermediates, the method allowed preparation of different derivatives derived in the C3-position.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10401 - Organic chemistry

Project

<a href="/en/project/FV20250" target="_blank" >FV20250: Modern methods for the synthesis of quinolones for pharmaceutical intermediates</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

SYNLETT

ISSN

0936-5214

e-ISSN

—

Volume of the periodical

31

Issue of the periodical within the volume

9

Country of publishing house

DE - GERMANY

Number of pages

5

Pages from-to

911-915

UT code for WoS article

000536560600017

EID of the result in the Scopus database

2-s2.0-85085307582