Electropolymerization of chitosan in the presence of CuNPs on the surface of a copper electrode: an advanced nanocomposite for the determination of mefenamic acid and indomethacin in human plasma samples and prevention of drug poisoning
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F20%3A73603910" target="_blank" >RIV/61989592:15310/20:73603910 - isvavai.cz</a>
Result on the web
<a href="https://pubs.rsc.org/en/content/articlelanding/2020/AY/C9AY02789K#!divAbstract" target="_blank" >https://pubs.rsc.org/en/content/articlelanding/2020/AY/C9AY02789K#!divAbstract</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c9ay02789k" target="_blank" >10.1039/c9ay02789k</a>
Alternative languages
Result language
angličtina
Original language name
Electropolymerization of chitosan in the presence of CuNPs on the surface of a copper electrode: an advanced nanocomposite for the determination of mefenamic acid and indomethacin in human plasma samples and prevention of drug poisoning
Original language description
An innovative method was introduced for the electro-polymerization of chitosan on the surface of a copper electrode. Two electrochemical sensors for the detection and determination of indomethacin and mefenamic acid in human plasma samples were constructed based on copper nanoparticles (CuNPs) and poly-chitosan-modified CuNPs, respectively. The electrochemical behaviors of the CuNP-modified copper electrode (CuE) and poly-chitosan-doped CuNP-modified copper electrode (P(CS)-CuNP-CuE) were investigated using differential pulse voltammetry and cyclic voltammetry techniques. The electrochemical results show that CuNPs and P(CS)-CuNPs lead to increased oxidation peak current by the adsorption of indomethacin. According to the obtained results, we inferred that the linear range and low limit of quantification (LLOQ) were 1 nM to 10 mM and 1 nM, respectively.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Analytical Methods
ISSN
1759-9660
e-ISSN
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Volume of the periodical
12
Issue of the periodical within the volume
9
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
1212-1217
UT code for WoS article
000519116000004
EID of the result in the Scopus database
2-s2.0-85081385047