Ratiometric pH-Responsive F-19 Magnetic Resonance Imaging Contrast Agents Based on Hydrazone Switches

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F22%3A73615122" target="_blank" >RIV/61989592:15310/22:73615122 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26620/22:PU144125
Result on the web
<a href="https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.1c04978" target="_blank" >https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.1c04978</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.analchem.1c04978" target="_blank" >10.1021/acs.analchem.1c04978</a>

Result language
angličtina
Original language name
Ratiometric pH-Responsive F-19 Magnetic Resonance Imaging Contrast Agents Based on Hydrazone Switches
Original language description
Hydrazone-based molecular switches serve as eflicient ratiometric pH-sensitive agents that can be tracked with F-19 NMR/MRI and H-1 NMR. Structural changes induced between pH 3 and 4 lead to signal appearance and disappearance at H-1 and F-19 NMR spectra allowing ratiometric pH measurements. The most pronounced are resonances of the CF3 group shifted by 1.8 ppm with F-19 NMR and a hydrazone proton shifted by 2 ppm with H-1 NMR.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry

Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)