Synthesis of Unsymmetrical 1,1’-Bibenzimidazoles via an N-Amination Reaction Forming the Key N-N Bond
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F22%3A73615707" target="_blank" >RIV/61989592:15310/22:73615707 - isvavai.cz</a>
Result on the web
<a href="https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/slct.202203144" target="_blank" >https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/slct.202203144</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/slct.202203144" target="_blank" >10.1002/slct.202203144</a>
Alternative languages
Result language
angličtina
Original language name
Synthesis of Unsymmetrical 1,1’-Bibenzimidazoles via an N-Amination Reaction Forming the Key N-N Bond
Original language description
The novel synthesis of unsymmetrical 1,1’-bibenzimidazoles is described. The key N−N bond was introduced on 1H-benzimidazole or 1H-benzimidazole-2-sulfonic acid by N-amination with hydroxylamine-O-sulfonic acid (HASA). The precursors, 1-[(2-nitrophenyl)amino]-1H-benzimidazoles, were prepared by nucleophilic aromatic substitution of 1-fluoro-2-nitrobenzene with 1H-benzimidazole-1-amines. The synthesis was demonstrated on 11 novel 1,1’-bibenzimidazoles, which were prepared in the final step by one-pot reduction/cyclization with DMF or DMA acetals under mild acidic conditions in good overall yields.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10401 - Organic chemistry
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ChemistrySelect
ISSN
2365-6549
e-ISSN
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Volume of the periodical
7
Issue of the periodical within the volume
38
Country of publishing house
DE - GERMANY
Number of pages
4
Pages from-to
"e202203144-1"-"e202203144-4"
UT code for WoS article
000865566700001
EID of the result in the Scopus database
2-s2.0-85139906917