The morphological and functional ultrastructure of cells in preimplantation embryos
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F23%3A73622663" target="_blank" >RIV/61989592:15310/23:73622663 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17110/23:A2402N9Q
Result on the web
<a href="http://www.elis.sk/download_file.php?product_id=8083&session_id=ji4p4pt495php9k5oeqb5uqtj0" target="_blank" >http://www.elis.sk/download_file.php?product_id=8083&session_id=ji4p4pt495php9k5oeqb5uqtj0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4149/gpb_2023011" target="_blank" >10.4149/gpb_2023011</a>
Alternative languages
Result language
angličtina
Original language name
The morphological and functional ultrastructure of cells in preimplantation embryos
Original language description
Cells of pre-implantation embryos are equipped with many morphological and functional systems through which they can synthesize specific proteins and effectively ensure the protection of early embryonic development. Here we present evidence for the existence of these systems in morphologically normal and abnormal bovine blastocyst stage embryos in vivo at the ultrastructural and actin cytoskeleton levels. The appearance of organelles in the trophectoderm and inner cell mass (ICM) cells, responsible for their synthetic activities and their role in the development of early bovine embryos are described. We point out the importance of endocytic processes and the participation of extracellular vesicles in the formation of intercellular contacts and homeostasis of the embryo microenvironment. Several changes in the ultrastructural morphology of embryos produced by different methods (ICSI, parthenogenetic AC/DC electrical activation, IVF with separated sperm) and freezing/thawed embryos are described. We also show alterations occurred in the organelles after viral contamination of embryos with BHV-1 and BVDV viruses. Recorded changes in organelles and appearance of cellular autophagic structures (vesicles, multivesicular bodies and autophagolysosomes) may negatively affect embryo metabolism and lead to the emergence of pathological processes in trophectoderm and ICM cells of preimplantation embryos.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10604 - Reproductive biology (medical aspects to be 3)
Result continuities
Project
<a href="/en/project/QK22010270" target="_blank" >QK22010270: Management optimalization of individual reproduction performance in dairy cattle</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
GENERAL PHYSIOLOGY AND BIOPHYSICS
ISSN
0231-5882
e-ISSN
1338-4325
Volume of the periodical
42
Issue of the periodical within the volume
4
Country of publishing house
SK - SLOVAKIA
Number of pages
15
Pages from-to
307-321
UT code for WoS article
001039331300001
EID of the result in the Scopus database
2-s2.0-85164759234