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Intraocular pressure response to gradual onset of extreme normobaric hypoxia

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F24%3A73625324" target="_blank" >RIV/61989592:15310/24:73625324 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15510/24:73625324

  • Result on the web

    <a href="https://www.minervamedica.it/en/journals/medicina-dello-sport/article.php?cod=R26Y2024N01A0037" target="_blank" >https://www.minervamedica.it/en/journals/medicina-dello-sport/article.php?cod=R26Y2024N01A0037</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.23736/S0025-7826.24.04397-7" target="_blank" >10.23736/S0025-7826.24.04397-7</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Intraocular pressure response to gradual onset of extreme normobaric hypoxia

  • Original language description

    BACKGROUND: During many sports, the organism is exposed to hypoxia. Exposure to hypoxia, such as staying at high altitudes, affects intraocular pressure (IOP), which is one of the most monitored parameters connected with glaucoma. This paper assesses the IOP response to a gradual onset of normobaric hypoxia and its acute termination. METHODS: Thirty-six subjects (2911 years) performed the complete test. The observed parameters were IOP, arterial oxygen saturation and corneal thickness (CT). After measurements in normoxia, subjects entered a normobaric hypoxic chamber with a simulated altitude of 2000 m which increased up to 5000 m during 77±7 min. After exposure (18±2 min) in the final altitude, the subjects left the chamber. RESULTS: The IOP significantly dropped after leaving the chamber up to 15.7±2.7 mmHg in comparison with the simulated altitude 5000 m (17.5±3.4 mmHg). The step change from normoxia to a simulated altitude (2000 m) and its gradual increase up to 5000 m did not affect IOP significantly. The CT did not change during the experiment. CONCLUSIONS: Gradual increase in hypoxia over tens of minutes does not affect IOP significantly, whereas a sudden departure from the hypoxic chamber with a simulated altitude of 5000 m causes significant changes in IOP. This IOP variation could be potentially health issue e.g. for glaucoma patients.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30207 - Ophthalmology

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    MEDICINA DELLO SPORT

  • ISSN

    0025-7826

  • e-ISSN

    1827-1863

  • Volume of the periodical

    77

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    IT - ITALY

  • Number of pages

    11

  • Pages from-to

    37-47

  • UT code for WoS article

    001229402100013

  • EID of the result in the Scopus database

    2-s2.0-85189703930