Rates of successful conceptions according to COVID-19 vaccination status: Data from the Czech Republic

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F25%3A73633952" target="_blank" >RIV/61989592:15310/25:73633952 - isvavai.cz</a>

Result on the web

<a href="https://journals.sagepub.com/doi/epub/10.1177/09246479251353384" target="_blank" >https://journals.sagepub.com/doi/epub/10.1177/09246479251353384</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/09246479251353384" target="_blank" >10.1177/09246479251353384</a>

Result language

angličtina

Original language name

Rates of successful conceptions according to COVID-19 vaccination status: Data from the Czech Republic

Original language description

Background Adverse effects of COVID-19 vaccination on human menstrual cycle characteristics have been observed, but limited data are available on the relationship between COVID-19 vaccination status and birth rates.Objectives Therefore, we used nationwide data from the Czech Republic to examine rates of successful conceptions (SCs), that is, conceptions leading to live births 9 months later, for women who were either vaccinated or unvaccinated against COVID-19 before SC.Methods Summary monthly COVID-19 vaccination and birth data for women in the Czech Republic aged 18-39 years were retrieved for the period from January 2021 to December 2023. The numbers of SCs per month per 1000 women were calculated for preconception-vaccinated or unvaccinated women, respectively, as well as the number of SCs per month per 1000 women for all women aged 18-39 years.Results During the study period, there were approximately 1,300,000 women aged 18-39 years in the Czech Republic, and the proportion of COVID-19-vaccinated women increased from January 2021 until reaching a steady state of around 70% by the end of 2021. At least from June 2021, SCs per 1000 women were considerably lower for women who were vaccinated, compared to those that were unvaccinated, before SC. Furthermore, SC rates for the vaccinated group were much lower than expected based on their proportion of the total population.Conclusions In the Czech Republic, SC rates were substantially lower for women vaccinated against COVID-19 before SC than for those who were not vaccinated. These hypothesis-generating and preliminary results call for further studies of the potential influence of COVID-19 vaccination on human fecundability and fertility.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30214 - Obstetrics and gynaecology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

INTERNATIONAL JOURNAL OF RISK &amp; SAFETY IN MEDICINE

ISSN

0924-6479

e-ISSN

1878-6847

Volume of the periodical

36

Issue of the periodical within the volume

4

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

5

Pages from-to

302-306

UT code for WoS article

001511401300001

EID of the result in the Scopus database

2-s2.0-105020456231