Plasma metallothionein levels in lead poisoned child.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F05%3A00086472" target="_blank" >RIV/62156489:43210/05:00086472 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Plasma metallothionein levels in lead poisoned child.

Original language description

A 11-year-old girl was referred to the hospital by her general practitioner because of abdominal pain, vomiting, dark colour of tongue, low intake of fluid and food, and abnormal laboratory results (bilirubin 55_mol/l, ast 2.94_kat/l, alt 3.46_kat/l, haemoglobin 86 g/l). Blood film exhibited basophilic stippling, prompting for investigation of lead poisoning. Blood lead levels were measured by automated graphite furnace aas (varian). Plasma metallothionein levels were measured by electroanalytical technique--voltametric Brdicka reaction. In time of admission, the blood lead was 648_g/l, and metallothionein 153 _mol/l (normal values below 10_mol/l). Chelation therapy by EDTA was administred for five consecutive days. During the course of therapy the b-Pb decreased to 360 _g/l, u-Pb increased to 6019_g/24 h, p-metallothionein increased to 276_mol/l. After 5 days of chelation treatment, the b-Pb increased (535_g/l), p-metallothionen decreased (147_mol/l). The source of 6 months lead expos

Czech name

Hodnoty metalothioneinu v plazmě dítěte otráveného olovem

Czech description

A 11-year-old girl was referred to the hospital by her general practitioner because of abdominal pain, vomiting, dark colour of tongue, low intake of fluid and food, and abnormal laboratory results (bilirubin 55_mol/l, ast 2.94_kat/l, alt 3.46_kat/l, haemoglobin 86 g/l). Blood film exhibited basophilic stippling, prompting for investigation of lead poisoning. Blood lead levels were measured by automated graphite furnace aas (varian). Plasma metallothionein levels were measured by electroanalytical technique--voltametric Brdicka reaction. In time of admission, the blood lead was 648_g/l, and metallothionein 153 _mol/l (normal values below 10_mol/l). Chelation therapy by EDTA was administred for five consecutive days. During the course of therapy the b-Pb decreased to 360 _g/l, u-Pb increased to 6019_g/24 h, p-metallothionein increased to 276_mol/l. After 5 days of chelation treatment, the b-Pb increased (535_g/l), p-metallothionen decreased (147_mol/l). The source of 6 months lead expos

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CG - Electrochemistry

OECD FORD branch

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Project

<a href="/en/project/GP525%2F04%2FP132" target="_blank" >GP525/04/P132: Study of protection mechanisms for stress-induced by heavy metals</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Toxicology Letters

ISSN

0378-4274

e-ISSN

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Volume of the periodical

158

Issue of the periodical within the volume

Suppl. 1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

2

Pages from-to

"S156"-"S157"

UT code for WoS article

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EID of the result in the Scopus database

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