Metallothionein - tumour disease marker?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F05%3A00086817" target="_blank" >RIV/62156489:43210/05:00086817 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Metallothionein - tumour disease marker?

Original language description

Number of authors have concerned with electrochemical analysis of metallothionein. Recently new electroanalytical techniques enabling determination of MT at picomole level has been suggested. The aim of the presented work was to show advantages and disadvantages of the different electrochemical procedures, which are commonly used for the detection of MT -- i) cyclic voltammetry, ii) differential pulse voltammetry, and iii) Brdicka reaction. Primarily we aimed on improvement of the mentioned techniques.Using of reducing agent (tris(2-carboxyethyl)phosphine) and combination of the mentioned method with adsorptive transfer stripping technique (AdTS) were the main improvements of the voltammetric method. The detection limits of metallothionein measured bycyclic voltammetry (CV), differential pulse voltammetry (DPV) and DPV Brdicka reaction were 0.5 pmol, 4 fmol and 10 amol, respectively. In addition AdTS DPV Brdicka reaction was used for the determination of metallothionein in human bloo

Czech name

Metalotionein - marker nádorového onemocnění?

Czech description

Number of authors have concerned with electrochemical analysis of metallothionein. Recently new electroanalytical techniques enabling determination of MT at picomole level has been suggested. The aim of the presented work was to show advantages and disadvantages of the different electrochemical procedures, which are commonly used for the detection of MT -- i) cyclic voltammetry, ii) differential pulse voltammetry, and iii) Brdicka reaction. Primarily we aimed on improvement of the mentioned techniques.Using of reducing agent (tris(2-carboxyethyl)phosphine) and combination of the mentioned method with adsorptive transfer stripping technique (AdTS) were the main improvements of the voltammetric method. The detection limits of metallothionein measured bycyclic voltammetry (CV), differential pulse voltammetry (DPV) and DPV Brdicka reaction were 0.5 pmol, 4 fmol and 10 amol, respectively. In addition AdTS DPV Brdicka reaction was used for the determination of metallothionein in human bloo

Type

D - Article in proceedings

CEP classification

CG - Electrochemistry

OECD FORD branch

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Project

<a href="/en/project/GP525%2F04%2FP132" target="_blank" >GP525/04/P132: Study of protection mechanisms for stress-induced by heavy metals</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

XLVIII. Zjazd Polskiego Towarzystwa Chemicznego i Stowarzyszenia Inzynierow i Technikow Przemyslu Chemicznego

ISBN

83-89936-07-0

ISSN

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e-ISSN

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Number of pages

1

Pages from-to

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Publisher name

PUH BETAGRAF Poznaň

Place of publication

Poznaň, Poland

Event location

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Event date

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Type of event by nationality

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UT code for WoS article

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