The Image of Exocytosis during Neutrophils and Macrophages Phagocytic Activities in Inflammation of Mammary Gland Triggered by Experimental Staphylococcus aureus Infection
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F06%3A00092683" target="_blank" >RIV/62156489:43210/06:00092683 - isvavai.cz</a>
Alternative codes found
RIV/00027162:_____/06:#0000050
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The Image of Exocytosis during Neutrophils and Macrophages Phagocytic Activities in Inflammation of Mammary Gland Triggered by Experimental Staphylococcus aureus Infection
Original language description
The experiments were carried out in five clinically normal virgin heifers. Neutrophils as well as macrophages underwent a classic exocytosis accompanied by translocation of lysosomal granules. The granules filled the protuberances of the plasmalemma andafter the protuberances separated from the cell, they entered the extracellular space in the shape of round bodies of different sizes. After exocytosis, neutrophils displayed a smaller nucleus/cytoplasm ratio, a greater chromatin density of the nucleus,and an overall smaller size. Macrophages underwent cytolysis that was accompanied by extrusion of granules, phagosomes and phagolysosomes containing phagocytosed bacteria or apoptotic neutrophils. Nevertheless, macrophages often underwent cytolysis at the site of inflammation.
Czech name
Obraz exocytózy během fagocytárních aktivit neutrofilů a makrofágů u zánětu mléčné žlázy vyvolaného experimentální infekcí Staphylococcus aureus.
Czech description
Pokusy byly realizovány na 5 klinicky zdravých jalovicích. Neutrofily a makrofáfy podstupovaly klasickou exocytózu doprovázenou translokací lysosomálních granulí. Granule vyplňovaly protuberance plasmalemy a poté se oddělovaly od buněk a vstupovaly do extracelulárního prostoru, ve tvary okrouhlých tělísek různé velikosti. Po exocytóze, neutrofily měly nízký nukleo/cytoplazmatický poměr, vysokou denzitu nukleárního chromatinu a menšíh velikosti. Makrofágy podstupovaly cytolýzu, jež byla doprovázena extruzí granulí, fagosomů a fagolysosomů obsahujících fagocytované bakterié a apoptotické neutrofily. Nicméně, makrofágy často podstupovaly cytolýzu právě v místě zánětu.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2006
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Anatomia, histologia, embryologia
ISSN
0340-2096
e-ISSN
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Volume of the periodical
35
Issue of the periodical within the volume
35
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
171-178
UT code for WoS article
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EID of the result in the Scopus database
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