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Electrochemical study of doxorubicin interaction with different sequences of double stranded oligonucleotides, Part II

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F12%3A00182656" target="_blank" >RIV/62156489:43210/12:00182656 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11310/12:10126257 RIV/00216305:26620/12:PU95570 RIV/00216224:14310/12:00060307 RIV/00216208:11130/12:8023 RIV/00064203:_____/12:8023

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Electrochemical study of doxorubicin interaction with different sequences of double stranded oligonucleotides, Part II

  • Original language description

    Interaction of low molecular weight compounds with DNA is one of general mechanisms utilized for an effective anticancer therapy. The anthracycline doxorubicin is one of the drugs that represent the compound with such effect. In our previous work [Hyneket al., Int. J. Electrochem, Sci. 7 (2012) xx] the electrochemical behaviour of doxorubicin interaction with single stranded ODN by using adsorptive transfer stripping square wave voltammetry was described. This paper is focused on the study of interaction of doxorubicin with double stranded ODNs (dsODNs) using the same technique. Here, we used four dsODNs possessing different primary structuresand observed the changes in their electrochemical behaviour after their treatment with three concentrations ofdoxorubicin for 5 hours. The changes found are discussed and differences in behaviours of individual dsODNs described and associated with their structure.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CB - Analytical chemistry, separation

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Electrochemical Science

  • ISSN

    1452-3981

  • e-ISSN

  • Volume of the periodical

    7

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    RS - THE REPUBLIC OF SERBIA

  • Number of pages

    16

  • Pages from-to

    34-49

  • UT code for WoS article

  • EID of the result in the Scopus database