Metallothionein electrochemically determined using Brdicka reaction as a promising blood marker of head and neck malignant tumours

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F12%3A00184859" target="_blank" >RIV/62156489:43210/12:00184859 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/12:10126270 RIV/00216224:14110/12:00059527 RIV/00216208:11130/12:8025 RIV/00216305:26620/12:PU97469 RIV/00064203:_____/12:8025
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Metallothionein electrochemically determined using Brdicka reaction as a promising blood marker of head and neck malignant tumours
Original language description
There are more than half of million patients who fall ill with head and neck carcinoma per year, which 6 % of annually newly diagnosed malignant diseases in the world. Group of head and neck tumours includes tumours occurring in the upper respiratory tract and upper digestive tract. They include tumours occurring in the area of oral cavity, tumours of hard and soft palate, gingivae and tongue. However, suitable markers in the case of head and neck carcinoma have not been satisfactory identified. Metallothioneins as a group of proteins with unknown but important role in development of a tumour can be assumed as a potential marker. Therefore, electrochemical monitoring of metallothionein levels in patients suffering from primary malignant tumour in headand neck area and examination of a suitability of electrochemical detection as a technique to be used in clinical practise are the most important aims of this study. Differential pulse voltammetry Brdicka reaction was optimized (time of a
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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