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Lead ions encapsulated in liposomes and their effect on Staphylococcus aureus

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F13%3A00213005" target="_blank" >RIV/62156489:43210/13:00213005 - isvavai.cz</a>

  • Alternative codes found

    RIV/62157124:16270/13:43872367

  • Result on the web

    <a href="http://dx.doi.org/10.3390/ijerph10126687" target="_blank" >http://dx.doi.org/10.3390/ijerph10126687</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/ijerph10126687" target="_blank" >10.3390/ijerph10126687</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Lead ions encapsulated in liposomes and their effect on Staphylococcus aureus

  • Original language description

    The aim of the study was the preparation of a liposome complex with encapsulated lead ions, which were electrochemically detected. In particular, experiments were focused on the potential of using an electrochemical method for the determination of free and liposome-encapsulated lead and determination of the encapsulation efficiency preventing the lead toxicity. Primarily, encapsulation of lead ions in liposomes and confirmation of successful encapsulation by electrochemical methods was done. Further, the reduction effect of the liposome matrix on the detected electrochemical signal was monitored. Besides encapsulation itself, comparison of toxicity of free lead ions and lead ions encapsulated in liposome was tested. The calculated IC50 values for evaluating the lead cytotoxicity showed significant differences between the lead enclosed in liposomes (28 uM) and free lead ions (237 uM). From the cytotoxicity studies on the bacterial strain of S. aureus it was observed that the free lead i

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>

  • Continuities

    O - Projekt operacniho programu

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Environmental Research and Public Health

  • ISSN

    1660-4601

  • e-ISSN

  • Volume of the periodical

    10

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    14

  • Pages from-to

    6687-6700

  • UT code for WoS article

    330219600026

  • EID of the result in the Scopus database