Liposomes as drug carriers and their characterization using different analytical methods
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F13%3A43908865" target="_blank" >RIV/62156489:43210/13:43908865 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26620/13:PU125824
Result on the web
<a href="https://mnet.mendelu.cz/mendelnet2013/mnet_2013_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2013/mnet_2013_full.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Liposomes as drug carriers and their characterization using different analytical methods
Original language description
The physicochemical properties of liposomes are significantly affected by the composition of phospholipid bilayer; differences in composition allow the use of liposomes for analytical purposes and for therapeutic purposes. One of the most used componentsof phospholipid bilayer is cholesterol. Its concentration plays a significant role in the behaviour of liposomes. This study points to changes in the properties of liposomes and its influence on encapsulated doxorubicin according to the content of cholesterol in the phospholipid bilayer. The influence of SDS addition to liposomal variants was also evaluated. Three variants of liposomes differing in various concentrations of cholesterol were assessed. Firstly, the toxicity of all types of liposomal doxorubicin was evaluated and it was found that the content of cholesterol increases the IC50 values of encapsulated doxorubicin in liposome. The highest concentration of cholesterol in liposome increased the IC50 value even four times compar
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
MendelNet 2013: Proceedings of International PhD Students Conference
ISBN
978-80-7375-908-7
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
913-918
Publisher name
Mendelova univerzita v Brně
Place of publication
Brno
Event location
Brno
Event date
Nov 20, 2013
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000366464800161