Fluorescence resonance energy transfer between green fluorescent protein and doxorubicin enabled by DNA nanotechnology
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F14%3A43908666" target="_blank" >RIV/62156489:43210/14:43908666 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26620/14:PU126725
Result on the web
<a href="http://dx.doi.org/10.1002/elps.201400166" target="_blank" >http://dx.doi.org/10.1002/elps.201400166</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/elps.201400166" target="_blank" >10.1002/elps.201400166</a>
Alternative languages
Result language
angličtina
Original language name
Fluorescence resonance energy transfer between green fluorescent protein and doxorubicin enabled by DNA nanotechnology
Original language description
DNA nanotechnology is a rapidly growing research area, where DNA may be used for wide range of applications such as construction of nanodevices serving for large scale of diverse purposes. Likewise a panel of various purified fluorescent proteins is investigated for their ability to emit their typical fluorescence spectra under influence of particular excitation. Hence these proteins may form ideal donor molecules for assembly of fluorescence resonance emission transfer (FRET) constructions. To extend the application possibilities of fluorescent proteins, while using DNA nanotechnology, we developed nanoconstruction comprising green fluorescent protein (GFP) bound onto surface of surface active nanomaghemite and functionalized with gold nanoparticles.We took advantage of natural affinity between gold and thiol moieties, which were modified to bind DNA fragment. Finally we enclosed doxorubicin into fullerene cages. Doxorubicin intercalated in DNA fragment bound on the particles and thu
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electrophoresis
ISSN
0173-0835
e-ISSN
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Volume of the periodical
35
Issue of the periodical within the volume
23
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
3290-3301
UT code for WoS article
000345972900002
EID of the result in the Scopus database
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