Evaluation of apoptosis and necrosis of peritoneal macrophages in rats after injection of zinc chelates into abdominal cavity

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F15%3A43906916" target="_blank" >RIV/62156489:43210/15:43906916 - isvavai.cz</a>
Result on the web
<a href="https://mnet.mendelu.cz/mendelnet2015/articles/67_vavrova_1182.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2015/articles/67_vavrova_1182.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Evaluation of apoptosis and necrosis of peritoneal macrophages in rats after injection of zinc chelates into abdominal cavity
Original language description
Aim of this study was to evaluate the influence of zinc chelates injected into abdominal cavity on viability of peritoneal macrophages. Three organic acids (EDTA, DTPA, NTA) were used as zinc carriers. 24 female rats were employed in this study. The ratswere divided into 5 groups: 6 received intraperitoneal injection of 2 mL 40 mM Zn-EDTA (group E), 6 received intraperitoneal injection of 2 mL 40 mM Zn-DTPA (group D), 6 rats received intraperitoneal injection of 40 mM 2 mL Zn-NTA (group N), 3 rats received 2 mL of normal saline (group K4-6) and 3 rats (group K1-3 for control) were intact. On the day after injection all rats were sacrificed and peritoneal lavages were performed and cell viability analysis was done. The macrophages were divided in two morphologically different groups - group of smaller monocytes-like macrophages (ML) with kidney-shaped nuclei and pseudopodia on their surface, and a group of macrophages with spherical nuclei and many vacuoles in the cytoplasm (vacuolized
Czech name
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Czech description
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Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
MendelNet 2015: Proceedings of International PhD Students Conference
ISBN
978-80-7509-363-9
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
600-603
Publisher name
Mendelova univerzita v Brně
Place of publication
Brno
Event location
Brno
Event date
Nov 11, 2015
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000366466100113

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