Differences in urinary proteins related to surgical margin status after radical prostatectomy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F15%3A43907631" target="_blank" >RIV/62156489:43210/15:43907631 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21230/15:00233645 RIV/00216208:11130/15:10315379 RIV/00216305:26620/15:PU118496 RIV/00064203:_____/15:10315379
Result on the web
<a href="http://dx.doi.org/10.3892/or.2015.4322" target="_blank" >http://dx.doi.org/10.3892/or.2015.4322</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3892/or.2015.4322" target="_blank" >10.3892/or.2015.4322</a>
Alternative languages
Result language
angličtina
Original language name
Differences in urinary proteins related to surgical margin status after radical prostatectomy
Original language description
Presented exploratory pilot study was aimed at evaluation of proteins present in urinary specimens collected from prostate cancer suffering subjects after radical prostatectomy, divided into two experimental cohorts: positive (n=15) and negative (n=15) surgical margins (PSM/NSM). The presence of PSM suggests inadequate cancer clearance and the possible need for additional treatment. Proper identification of these risk-patients is therefore of a paramount importance. Total protein profiles were firstly identified by using SDS-PAGE and compared by using partial least square discrimination analysis (PLS-DA), which revealed differences in molecular weights of 80-99 and 150-235 kDa between the experimental groups. For further identification of proteins, comparative proteomic technologies were employed. Two-dimensional gel electrophoresis with subsequent identification of protein spots by using MALDI-TOF mass fingerprinting revealed differential expression of proteins between NSM/PSM cohorts
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Oncology Reports
ISSN
1021-335X
e-ISSN
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Volume of the periodical
34
Issue of the periodical within the volume
6
Country of publishing house
GR - GREECE
Number of pages
9
Pages from-to
3247-3255
UT code for WoS article
000364617000050
EID of the result in the Scopus database
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