All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Physicochemical Investigation of Stability of Apoferritin with Encapsulated Doxorubicin

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F16%3A43910231" target="_blank" >RIV/62156489:43210/16:43910231 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216305:26620/16:PU122771 RIV/00216208:11310/16:10372820

  • Result on the web

    <a href="https://mnet.mendelu.cz/mendelnet2016/mnet_2016_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2016/mnet_2016_full.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Physicochemical Investigation of Stability of Apoferritin with Encapsulated Doxorubicin

  • Original language description

    The many negative side effects of drugs used for treatment of highly diverse diseases, such as cancer, lead in recent years to the development of ways how to target the drug selectively to the diseased tissue while avoiding the healthy cells. Nanocarriers, made from various materials, can serve as a suitable platform for this targeted drug delivery. Herein, we evaluate the long-term stability of nanocarrier based on ubiquitous protein apoferritin with encapsulated doxorubicin. Various properties of the nanocarrier were observed over the course of 12 weeks while stored at various temperatures, such as premature drug release, optical properties of the encapsulated drug, nanocarrier size and surface zeta potential. The nanocarrier showed very good stability for up to 12 weeks with the best results observed with nanocarrier prepared in water and stored at dark at 4 oC.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CB - Analytical chemistry, separation

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA14-18344S" target="_blank" >GA14-18344S: Development of nanoparticle-based cytostatics and enzymes for enhanced chemotherapy of human neuroblastomas and study of mechanisms of their action</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    MendelNet 2016: Proceedings of International PhD Students Conference

  • ISBN

    978-80-7509-443-8

  • ISSN

  • e-ISSN

  • Number of pages

    6

  • Pages from-to

    966-971

  • Publisher name

    Mendelova univerzita v Brně

  • Place of publication

    Brno

  • Event location

    Brno

  • Event date

    Nov 9, 2016

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article

    000392968500173