Dual-color quantum dots-based simultaneous detection of HPV-HIV co-infection

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F18%3A43913349" target="_blank" >RIV/62156489:43210/18:43913349 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/18:00102718 RIV/00216305:26620/18:PU127621
Result on the web
<a href="https://doi.org/10.1016/j.snb.2017.11.074" target="_blank" >https://doi.org/10.1016/j.snb.2017.11.074</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.snb.2017.11.074" target="_blank" >10.1016/j.snb.2017.11.074</a>

Result language
angličtina
Original language name
Dual-color quantum dots-based simultaneous detection of HPV-HIV co-infection
Original language description
Human papillomavirus (HPV) and human immunodeficiency virus (HIV) are closely related infections; both diseases are mutually reinforcing due to the co-infection effects, which increase their clinical and epidemiological implications, raising urgent public health concerns. In the present study, a nano-system was developed for simultaneous detection of HPV and HIV targeting E6-HPV16 and Gag-HIV genes respectively. The target sequences from the samples of the patients suffering from head and neck cancer were isolated by magnetic glass particles (MGPs) and subsequently were hybridized with a mixture of the complementary probes attached to cadmium telluride quantum dots (CdTe QDs). Finally, the specific and successful binding was determined by an easy fluorescence analyses and was corroborated by PCR and electrochemistry. Red and green CdTe QDs were used for the dual-color detection of HPV and HIV respectively. Our nano-system can be applied as a proficient tool for the identification of HPV, HIV or both diseases simultaneously, getting a successful and high sensitivity system of detection.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry

Project
<a href="/en/project/LO1401" target="_blank" >LO1401: Interdisciplinary Research of Wireless Technologies</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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