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Gold nanoparticles as labels for immunochemical analysis using laser ablation inductively coupled plasma mass spectrometry

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F19%3A43915001" target="_blank" >RIV/62156489:43210/19:43915001 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216305:26620/19:PU131560 RIV/00216224:14310/19:00107331

  • Result on the web

    <a href="https://doi.org/10.1007/s00216-018-1300-7" target="_blank" >https://doi.org/10.1007/s00216-018-1300-7</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00216-018-1300-7" target="_blank" >10.1007/s00216-018-1300-7</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Gold nanoparticles as labels for immunochemical analysis using laser ablation inductively coupled plasma mass spectrometry

  • Original language description

    In this paper, we describe the labelling of antibodies by gold nanoparticles (AuNPs) with diameters of 10 and 60 nm with detection by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). Additionally, the AuNPs labelling strategy is compared with commercially available labelling reagents based on MeCAT (metal coded affinity tagging). Proof of principle experiments based on dot blot experiments were performed. The two labelling methods investigated were compared by sensitivity and limit of detection (LOD). The absolute LODs achieved were in the range of tens of picograms for AuNP labelling compared to a few hundred picograms by the MeCAT labelling.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

    <a href="/en/project/GA17-12774S" target="_blank" >GA17-12774S: Metal-nanopartcials based multilabeling for bioimaging</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Analytical and Bioanalytical Chemistry

  • ISSN

    1618-2642

  • e-ISSN

  • Volume of the periodical

    411

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    6

  • Pages from-to

    559-564

  • UT code for WoS article

    000456132700003

  • EID of the result in the Scopus database

    2-s2.0-85051727664