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Isolation of Monocytes from Bovine Blood for Purposes of Culture of Dendritic Cells

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F19%3A43916589" target="_blank" >RIV/62156489:43210/19:43916589 - isvavai.cz</a>

  • Alternative codes found

    RIV/00027162:_____/19:N0000133

  • Result on the web

    <a href="http://dx.doi.org/10.15414/jmbfs.2019.9.special.427-430" target="_blank" >http://dx.doi.org/10.15414/jmbfs.2019.9.special.427-430</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.15414/jmbfs.2019.9.special.427-430" target="_blank" >10.15414/jmbfs.2019.9.special.427-430</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Isolation of Monocytes from Bovine Blood for Purposes of Culture of Dendritic Cells

  • Original language description

    Monocytes comprise a population of mononuclear leukocytes. In this article, we compare methods for isolating monocytes and also their cultivation into dendritic cells. Bovine blood collected from the vena jugularis externa was used for the experiment. This blood was used for isolating monocytes based on density gradient of OptiPrep or Histopaque solutions. The results indicated that the more efficient method is isolation based on density gradient of the Histopaque solution and subsequent magnetic separation of the cells. The monocyte population was further cultivated for 72 h with IL-4 and GM-CSF. The cells were evaluated under a light microscope, and it was apparent that CD14-positive cells transformed to dendritic cells. The second method using the Histopaque solution and magnetic separation was more efficient for the subsequent culture of dendritic cells.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database

  • CEP classification

  • OECD FORD branch

    40201 - Animal and dairy science; (Animal biotechnology to be 4.4)

Result continuities

  • Project

    <a href="/en/project/QK1910212" target="_blank" >QK1910212: Modern methods of diagnosis, therapy and prevention of mastitis caused by Streptococcus uberis as a tool for designing targeted control programs in cows</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Microbiology, Biotechnology and Food Science

  • ISSN

    1338-5178

  • e-ISSN

  • Volume of the periodical

    9

  • Issue of the periodical within the volume

    Special Issue

  • Country of publishing house

    SK - SLOVAKIA

  • Number of pages

    4

  • Pages from-to

    427-430

  • UT code for WoS article

    000500544500014

  • EID of the result in the Scopus database

    2-s2.0-85083482487