Bacteriospermia and Male Infertility: Role of Oxidative Stress

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F22%3A43921557" target="_blank" >RIV/62156489:43210/22:43921557 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/978-3-030-89340-8_7" target="_blank" >https://doi.org/10.1007/978-3-030-89340-8_7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-030-89340-8_7" target="_blank" >10.1007/978-3-030-89340-8_7</a>

Result language
angličtina
Original language name
Bacteriospermia and Male Infertility: Role of Oxidative Stress
Original language description
Male infertility is one of the major challenging and prevalent diseases having diverse etiologies of which bacteriospermia play a significant role. It has been estimated that approximately 15% of all infertility cases are due to infections caused by uropathogens and in most of the cases bacteria are involved in infection and inflammation leading to the development of bacteriospermia. In response to bacterial load, excess infiltration of leukocytes in the urogenital tract occurs and concomitantly generates oxidative stress (OS). Bacteria may induce infertility either by directly interacting with sperm or by generating reactive oxygen species (ROS) and impair sperm parameters such as motility, volume, capacitation, hyperactivation. They may also induce apoptosis leading to sperm death. Acute bacteriospermia is related with another clinical condition called leukocytospermia and both compromise male fertility potential by OS-mediated damage to sperm leading to male infertility. However, bacteriospermia as a clinical condition as well as the mechanism of action remains poorly understood, necessitating further research in order to understand the role of individual bacterial species and their impact in male infertility.
Czech name
—
Czech description
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Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name
Oxidative Stress and Toxicity in Reproductive Biology and Medicine: A Comprehensive Update on Male Infertility. Volume I
ISBN
978-3-030-89339-2
Number of pages of the result
23
Pages from-to
141-163
Number of pages of the book
379
Publisher name
Springer Switzerland
Place of publication
Cham
UT code for WoS chapter
001022592500009

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