A color-tunable single-benzene fluorophore-based sensor for sensitive detection of palladium in solution and living cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F23%3A43923409" target="_blank" >RIV/62156489:43210/23:43923409 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/23:00133292
Result on the web
<a href="https://doi.org/10.1039/D3AN00046J" target="_blank" >https://doi.org/10.1039/D3AN00046J</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/d3an00046j" target="_blank" >10.1039/d3an00046j</a>

Result language
angličtina
Original language name
A color-tunable single-benzene fluorophore-based sensor for sensitive detection of palladium in solution and living cells
Original language description
Single-benzene fluorophores are bright and the smallest fluorochromes known so far. In single-benzene fluorophores, the fluorescence is mediated by the push/pull effect of substituting groups. Despite a plethora of advantageous properties, this group of molecules has not been extensively studied for design of high-performance fluorescent sensors of catalytic or enzymatic activities. Thus, herein, new fluorescent probes based on the Tsuji-Trost reaction were developed for the selective detection of palladium and other transition metals (platinum and gold) in an aqueous/organic mixed solvent with the sensitivity down to 2.5 nM (for palladium). The relative flexibility in the synthesis of these probes allows for facile color tuning of the emitted fluorescence. In this study, we have successfully utilized a yellow emission variant for sensitive detection of palladium under cell-free conditions and in living cells, validating its possible applicability for high-throughput optical sensing of catalysts for bioorthogonal chemistry under physiological conditions.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10608 - Biochemistry and molecular biology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)