Characterisation of peroxidase-like activity of thermally synthesized gold nanoparticles

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43510%2F16%3A43911128" target="_blank" >RIV/62156489:43510/16:43911128 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22330/17:43913731
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Characterisation of peroxidase-like activity of thermally synthesized gold nanoparticles
Original language description
The development of nanotechnologies has attracted a lot of interest since it brings new possibilities in the field of nanomedical applications, from diagnostic methods to targeted nanotransporters. Gold nanoparticles (AuNPs) belong to a group of nanomaterials with significant peroxidase-like activity. We have successfully synthesized AuNPs thermally over a range of temperatures from 20 to 100oC. The AuNPs size varied from 17 to 37 nm and the zeta potential was found to vary from-32 to-44 mV, in which the maximum absorption maximum was detected at 529 nm. Peroxidase-like activity was monitored in the presence of TMB (1 mM) and hydrogen peroxide (10 mM). The proposed system based on peroxidase-like activity was further evaluated in immune detection of human IgG, in which anti-IgG antibody was modified with AuNPs.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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