Impact of Species, Growth Conditions, and Plant Processing on the Phytochemistry and Antimicrobial Activity of Agrimonia Extracts

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43510%2F25%3A43927358" target="_blank" >RIV/62156489:43510/25:43927358 - isvavai.cz</a>

Alternative codes found

RIV/60461373:22330/25:43933110

Result on the web

<a href="https://doi.org/10.1002/cbdv.202501283" target="_blank" >https://doi.org/10.1002/cbdv.202501283</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/cbdv.202501283" target="_blank" >10.1002/cbdv.202501283</a>

Result language

angličtina

Original language name

Impact of Species, Growth Conditions, and Plant Processing on the Phytochemistry and Antimicrobial Activity of Agrimonia Extracts

Original language description

Agrimonia eupatoria L., a herb used in traditional medicine, contains numerous secondary metabolites with beneficial properties. However, its phytochemistry, and consequently bioactivity, can be strongly influenced by various cultivation and processing factors. This study evaluates the impact of growth locality, plant part, ontogenetic phase, and postharvest processing on the phytochemical composition and antimicrobial potential of two agrimony species: A. eupatoria and Agrimonia procera. A total of 94 herbal samples extracted with 40% aqueous ethanol were analyzed using ultrahigh-performance liquid chromatography and high-resolution tandem mass spectrometry and simultaneously tested against selected Gram-positive, Gram-negative, and anaerobic bacteria and yeasts. Targeted screening of bioactive polyphenols revealed significant differences between the agrimony species, with phloridzin and orientin/isoorientin identified as new potential chemotaxonomic markers. Notable differences were also observed between roots and aerial parts. Postharvest processing, particularly drying, proved to be another important factor, reducing the overall polyphenol content compared to fresh-frozen plant material. Although all extracts exhibited strong activity, especially against Gram-positive bacteria, the highest antimicrobial potential was observed in roots extracts rich in procyanidins and catechins. The findings of this study enhance the understanding of agrimony phytochemistry and its variability, thereby supporting the effective production of medicinal preparations with the desired therapeutic effects.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10611 - Plant sciences, botany

Project

<a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chemistry and Biodiversity

ISSN

1612-1872

e-ISSN

1612-1880

Volume of the periodical

22

Issue of the periodical within the volume

12

Country of publishing house

DE - GERMANY

Number of pages

15

Pages from-to

"e01283"

UT code for WoS article

001546177200001

EID of the result in the Scopus database

2-s2.0-105012739905