Comprehensive assessment of bioactive secondary metabolites in a set of aqueous extracts from agrimony (Agrimonia eupatoria L.)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F22%3A43925446" target="_blank" >RIV/60461373:22330/22:43925446 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Comprehensive assessment of bioactive secondary metabolites in a set of aqueous extracts from agrimony (Agrimonia eupatoria L.)

Original language description

Agrimony (Agrimonia eupatoria L.) is a medicinal plant widely used in traditional medicine. Nowadays, homemade herbal extracts are gaining growing popularity. Aqueous agrimony extracts are mainly used for rinsing wounds, alternatively, dried plant is used as tea. These products have positive effects on human health and body (antioxidant activity, anti-inflammatory effect or hepatoprotective effect) thanks to the content of several bioactive compounds such as flavonoids, phenolic acids or tannins. In this study, “homemade” aqueous extracts from agrimony herbs collected at different locations, differently processed (dried, fresh) and picked in various vegetation states were prepared and targeted screening of polyphenol compounds with the reversed phase ultra-high-performance liquid chromatography coupled with high-resolution tandem mass spectrometry (UHPLC-HRMS/MS) was carried out. For the purpose of aqueous extracts screening and interesting bioactive metabolites identification, an in-house spectral library of more than 500 polyphenolic compounds occurring in plants was created. In total, 62 compounds were identified. The samples did not differ significantly in the type of bioactive compounds, differences were only in the occurrence of some individual polyphenols depending on a geographical origin of respective sample. In the samples from the last vegetation state (senescence) was identified significantly less compounds and their profiles differed in comparison with other samples.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

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OECD FORD branch

10700 - Other natural sciences

Project

<a href="/en/project/LM2018100" target="_blank" >LM2018100: Infrastructure for Promoting Metrology in Food and Nutrition in the Czech Republic</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů