Role of WNT signaling in the pathogenesis of ameloblastoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F18%3A43876337" target="_blank" >RIV/62157124:16170/18:43876337 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Role of WNT signaling in the pathogenesis of ameloblastoma
Original language description
Ameloblastoma is the most common odontogenic tumor in humans. This tumor is mostly benign, but can invade local structures including bones. The reoccurrence after surgical treatment is very common. Here, we investigated the role of Frizzled6 (FZD6) in tumorigenesis of ameloblastoma. FZD6 is one of the receptors of WNT signaling pathway, which plays role in determination of planar cell polarity. We also investigated expression pattern of beta-catenin ? major activator in canonical WNT signaling pathway and a cell-cell adhesion regulator.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
40301 - Veterinary science
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů