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CTX-M-producing Escherichia coli in pigs from a Czech farm during production cycle

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F20%3A43878745" target="_blank" >RIV/62157124:16170/20:43878745 - isvavai.cz</a>

  • Alternative codes found

    RIV/62157124:16270/20:43878745 RIV/62157124:16810/20:43878745

  • Result on the web

    <a href="https://sfamjournals.onlinelibrary.wiley.com/doi/abs/10.1111/lam.13331" target="_blank" >https://sfamjournals.onlinelibrary.wiley.com/doi/abs/10.1111/lam.13331</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/lam.13331" target="_blank" >10.1111/lam.13331</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    CTX-M-producing Escherichia coli in pigs from a Czech farm during production cycle

  • Original language description

    We evaluated the prevalence and epidemiology of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli isolates in pigs during production cycle on a Czech farm with the history of previous use of ceftiofur. ESBL-producing E. Coli isolates were obtained from rectal swabs from pigs of different age groups (suckling piglets, weaned piglets, growers and sows). Collected samples were directly cultivated on MacConkey agar with cefotaxime (2 mg l(-1)), whereas intestinal swabs of slaughtered pigs and surface swabs from pig carcasses were also pre-enriched in buffered peptone water without antimicrobials before the cultivation. Clonal relationship of selected isolates was determined byXbaI pulse-field gel electrophoresis and multi-locus sequence typing. The transferability of plasmids carryingbla(CTX-M)genes was tested by conjugation experiments. From all examined samples, 141 (43 center dot 7%,n = 323) were positive for ESBL-producing E. coli. All ESBL-producing isolates showed resistance to multiple antimicrobials and were positive forbla(CTX-M)genes. Thebla(CTX-M-1)was carried by conjugative IncN/ST1 plasmids (c. 40-45 kb) while thebla(CTX-M-15)was located on conjugative F plasmids with F:18:A5:B1 formula (c. 165 kb). This study demonstrated the persistence of CTX-M-positiveE. coliisolates 2 months after banner of ceftiofur usage and indicated possible risk of transmission of these isolates to humans via the food chain.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    40301 - Veterinary science

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Letters in Applied Microbiology

  • ISSN

    0266-8254

  • e-ISSN

  • Volume of the periodical

    71

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    8

  • Pages from-to

    369-376

  • UT code for WoS article

    000542844500001

  • EID of the result in the Scopus database