Limitations of the current equine melanocytic tumour classification

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F23%3A43880566" target="_blank" >RIV/62157124:16170/23:43880566 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Limitations of the current equine melanocytic tumour classification
Original language description
Equine melanocytic tumours (EMT) are frequent in older grey horses. They are described as variously pigmented neoplasia, mainly located on the ventral tail and in the perineum, which can progress into generalised disease. Histopathologically, EMT can be divided into four types: melanocytic nevus (MN), dermal melanoma/melanomatosis (DM/DMT) and anaplastic malignant melanoma (AMM). However, recent studies suggest that this classification does not sufficiently reflect the biological behaviour of these tumours. This study aimed to classify EMTs diagnosed by routine HE staining with the aid of immunohistochemistry. EMTs from thirty horses were examined. The majority of the affected horses were grey, only three had other coat colours (black, perlino, chestnut). Twelve EMTs were classified as DM/DMT, eleven as MN and two as AMM. Five cases could not be classified. They originated from three horses with a single or multiple tumours which showed characteristics of both MN and DM/DMT and two horses in the early stage of the disease. The relatively high proportion of unclassified EMTs (3 out of 30 cases, 10%) indicate the need for improving/extending of the current classification.
Czech name
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Czech description
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Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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