Senecio ovatus poisoning in a horse - A case report.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F24%3A43881470" target="_blank" >RIV/62157124:16170/24:43881470 - isvavai.cz</a>

Alternative codes found

RIV/62157124:16270/24:43881470

Result on the web

<a href="https://vetmed.agriculturejournals.cz/pdfs/vet/2024/09/03.pdf" target="_blank" >https://vetmed.agriculturejournals.cz/pdfs/vet/2024/09/03.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17221/37/2024-VETMED" target="_blank" >10.17221/37/2024-VETMED</a>

Result language

angličtina

Original language name

Senecio ovatus poisoning in a horse - A case report.

Original language description

This study describes a case of poisoning by pyrrolizidine alkaloids in a horse. To the best of the author&apos;s knowledge, this is the first confirmed case of Senecio ovatus poisoning. A six-year-old 450-kg Irish cob mare was presented to the Equine Clinic of the University of Veterinary Sciences Brno (Czechia) with symptoms of hepatic encephalopathy, which progressively worsened with time despite intensive therapy and led to euthanasia. A complex diagnostic and therapeutic approach including the post-mortem patoanatomical and histopathological examination is described here. Regarding the histopathology of the liver, there was necrosis with haemorrhage, fatty changes and inflammation. A later inspection of the grazing area revealed the presence of Senecio ovatus (wood ragwort). A sensitive chromatographic method was used to determine the pyrrolizidine alkaloids and their metabolites in the plasma and the liver. In both of the samples, metabolites of pyrrolizidine alkaloids were detected. Although pyrrolizidine alkaloid poisoning was proven, the histopathological findings typical for this disease were absent. It is clear from our case that the histopathology in cases of poisoning by pyrrolizidine alkaloids may not always be conclusive.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40301 - Veterinary science

Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Veterinární medicína

ISSN

0375-8427

e-ISSN

1805-9392

Volume of the periodical

69

Issue of the periodical within the volume

9

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

329-336

UT code for WoS article

001328061800004

EID of the result in the Scopus database

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