Protein carbonyls and traditional biomarkers in pigs exposed to low-dose gamma-radiation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F13%3A43871983" target="_blank" >RIV/62157124:16270/13:43871983 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.rvsc.2012.09.002" target="_blank" >http://dx.doi.org/10.1016/j.rvsc.2012.09.002</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.rvsc.2012.09.002" target="_blank" >10.1016/j.rvsc.2012.09.002</a>

Result language
angličtina
Original language name
Protein carbonyls and traditional biomarkers in pigs exposed to low-dose gamma-radiation
Original language description
Response of pigs to irradiation manifested by production of protein carbonyls and adaptable enzymes was studied in two experiments. In one experiment, 10 mixed-sex pigs were exposed to 0.5 Gy whole body 60Co irradiation. In the other experiment, anotherbatch of 10 pigs was exposed to 1.0 Gy half-body irradiation. Unlike those exposed to half-body irradiation, the pigs exposed to whole-body irradiation showed significant increase in protein carbonyls by 73%, and a decrease in cholesterol by 25.7%, compared to the control group. In both cases of dose-dependent irradiation exposure, pigs showed a decrease in alanine aminotransferase activity compared with the control group. At the dose of 1 Gy, ALT activity decreased significantly by 27.7%. Aspartate aminotransferase activity in pigs after half-body irradiation decreased significantly by 65.5%. Although low doses of ionizing radiation were applied, monitoring of the above biochemical parameters helped define the pigs' biological response
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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