Molecular biology of beta-estradiol-estrogen receptor complex binding to estrogen response element and the effect on cell proliferation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F13%3A43872361" target="_blank" >RIV/62157124:16270/13:43872361 - isvavai.cz</a>

Alternative codes found

RIV/62156489:43210/13:43908660 RIV/00216305:26620/13:PU125788

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Molecular biology of beta-estradiol-estrogen receptor complex binding to estrogen response element and the effect on cell proliferation

Original language description

Group of estrogen pollutants, where the highest estrogen activity is reported at estradiol, is characterized by the fact that even at very low concentrations have potential to cause xenoestrogenic effects. During exposure of excessive amounts of estradiols may be produced undesirable effects resulting in the feminization of males of water organisms. The presence of estradiols in drinking water implies also a risk for the human population in the form of cancers of endocrine systems, abnormalities in reproduction or dysfunctions of neuronal and immune system. Currently, the research is focused mainly to uncover the relationship between the estrogen receptors binding affinity with an estrogen response element and estradiol. In this review we summarized facts about molecular biological principles of beta estradiol-estrogen receptor complex binding with estrogen response element and its successive effect on cancer genes expression.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

—

Project

—

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuroendocrinology Letters

ISSN

0172-780X

e-ISSN

—

Volume of the periodical

34

Issue of the periodical within the volume

Suppl. 2

Country of publishing house

US - UNITED STATES

Number of pages

7

Pages from-to

123-129

UT code for WoS article

000330901000019

EID of the result in the Scopus database

—