Antimicrobial Properties of Microparticles Based on Carmellose Cross-Linked by Cu2+ Ions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F15%3A43873515" target="_blank" >RIV/62157124:16270/15:43873515 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16170/15:43873515 RIV/62157124:16370/15:43873515
Result on the web
<a href="http://dx.doi.org/10.1155/2015/790720" target="_blank" >http://dx.doi.org/10.1155/2015/790720</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2015/790720" target="_blank" >10.1155/2015/790720</a>
Alternative languages
Result language
angličtina
Original language name
Antimicrobial Properties of Microparticles Based on Carmellose Cross-Linked by Cu2+ Ions
Original language description
Carmellose (CMC) is frequently used due to its high biocompatibility, biodegradability, and low immunogenicity for development of site-specific or controlled release drug delivery systems. In this experimental work, CMC dispersions in two different concentrations (1% and 2%) cross-linked by copper (II) ions (0.5, 1, 1.5, or 2.0 M CuCl2) were used to prepare microspheres with antimicrobial activity against Escherichia coli and Candida albicans, both frequently occurring pathogens which cause vaginal infections. The microparticles were prepared by an ionotropic gelation technique which offers the unique possibility to entrap divalent copper ions in a CMC structure and thus ensure their antibacterial activity. Prepared CMC microspheres exhibited sufficient sphericity. Both equivalent diameter and copper content were influenced by CMC concentration, and the molarity of copper (II) solution affected only the copper content results. Selected samples exhibited stable but pH-responsive behavio
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomed Research International
ISSN
2314-6133
e-ISSN
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Volume of the periodical
Neuveden
Issue of the periodical within the volume
2015
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
"Nestránkováno"
UT code for WoS article
000355513200001
EID of the result in the Scopus database
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