Environmental implications of fluoroquinolone exposure on aquatic ecosystems
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F15%3A43873841" target="_blank" >RIV/62157124:16270/15:43873841 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Environmental implications of fluoroquinolone exposure on aquatic ecosystems
Original language description
The manufacturing and the use of fluoroquinolones in animal and human medicine contribute to the dissemination of residues and byproducts into aquatic environments as dictated by the antibiotic's pharmacokinetic and physio-chemical properties and half-life among other factors. The objective was to create a concise review of the true ecotoxicological effects of fluoroquinolones on lifeforms and the impacts to aquatic ecosystems. High doses in toxicological assessment models show significant effects on embryo development, mortality rates and reproductive system abnormalities. At lower doses, the effects are less clear, as long term exposure at low doses and generational exposure are difficult to assess in natural environments. The multifactorial nature of ecotoxicological effects have proven difficult to fully extrapolate scientific models and in silico tests regarding different toxicity endpoints to the natural environment, however today's scientific evidence suggests an overall negative impact of fluoroquinolones on the aquatic environment.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
EH - Ecology - communities
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT14398" target="_blank" >NT14398: Bacterial resistance to fluoroquinolones, possibilities for its prevention and public health protection</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Sborník příspěvků XVII. konference mladých vědeckých pracovníků s mezinárodní účastí
ISBN
978-80-7305-758-9
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
81-83
Publisher name
Veterinární a farmaceutická univerzita Brno
Place of publication
Brno
Event location
Brno
Event date
May 27, 2015
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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