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Characterization of IncX plasmids carrying quinolone and beta-lactam resistance genes in Enterobacteriaceae from various sources and geographic areas

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F15%3A43873865" target="_blank" >RIV/62157124:16270/15:43873865 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Characterization of IncX plasmids carrying quinolone and beta-lactam resistance genes in Enterobacteriaceae from various sources and geographic areas

  • Original language description

    The aim of the study was to map the diversity of IncX plasmids carrying resistance genes to quinolones and beta-lactams in non-related Enterobacteriaceae from various sources and geographic areas and to identify the most prevalent types of these plasmids. A collection of 1800 Enterobacteriaceae isolates resistant to cefotaxime (2 mg/L) or with reduced susceptibility to ciprofloxacin (0.05 mg/L) were tested for IncX1-X4 plasmids using PCR. Isolates were tested for antibiotic resistance genes by PCR and sequencing. Isolates were identified using biochemical tests or MALDI-TOF and their relatedness was determined by pulsed-field gel electrophoresis (PFGE). Plasmid analysis included conjugation and transformation, sizing using S1-nuclease and PFGE, restriction analysis and hybridization. A total of 190 Enterobacteriaceae isolates (10.6%, n=1800) harboured at least one IncX subgroup. IncX1 subgroup was the most prevalent (107 isolates), followed by IncX2 (47), IncX4 (28) and IncX3 (17). Inc

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    EE - Microbiology, virology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Sborník příspěvků XVII. konference mladých vědeckých pracovníků s mezinárodní účastí

  • ISBN

    978-80-7305-758-9

  • ISSN

  • e-ISSN

  • Number of pages

    3

  • Pages from-to

    75-77

  • Publisher name

    Veterinární a farmaceutická univerzita Brno

  • Place of publication

    Brno

  • Event location

    Brno

  • Event date

    May 27, 2015

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article