Respiratory burst of phagocytes in bats compared with mice

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F19%3A43877691" target="_blank" >RIV/62157124:16270/19:43877691 - isvavai.cz</a>
Result on the web
<a href="https://fvhe.vfu.cz/files/Sbornik_KMVP_2019.pdf" target="_blank" >https://fvhe.vfu.cz/files/Sbornik_KMVP_2019.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Respiratory burst of phagocytes in bats compared with mice
Original language description
The heterotherm immune system undergoes significant variation in response to life cycle periodicity and torpor. As heterothermic bats are important reservoirs of zoonotic agents and modulation of immune activity can affect host-pathogen interactions, this work aimed at developing a suitable method for assessing heterotherm phagocyte activity. Chemiluminescence measurements using selected parameters offers a simple and reliable tool for comparing phagocyte activity. While time-related parameters (Tstart, Tpeak and Tend) of bat phagocyte activity varied with measurement temperature, with onset of respiratory burst at 38°C being quicker than at 25°C, quantitative value of phagocyte activity (Integral) was not influenced by measurement temperature. Further, homeotherm phagocyte activity parameters were more reduced at 25°C. Considering there was no influence of measurement temperature on total volume of heterotherm phagocyte activity, we suggest that parameters measured at 25°C are more representative of immune status adapted to physiological extremes at low body temperatures.
Czech name
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Czech description
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Project
<a href="/en/project/GA17-20286S" target="_blank" >GA17-20286S: Physiology of bat hibernation with respect to multistressor impacts</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
XXI. KONFERENCE MLADÝCH VĚDECKÝCH PRACOVNÍKŮ S MEZINÁRODNÍ ÚČASTÍ, Sborník příspěvků
ISBN
978-80-7305-820-3
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
140-142
Publisher name
Veterinární a farmaceutická univerzita Brno
Place of publication
Brno
Event location
Brno
Event date
May 22, 2019
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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