Measurement of phagocyte activity in heterotherms

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F20%3A43878811" target="_blank" >RIV/62157124:16270/20:43878811 - isvavai.cz</a>

Alternative codes found

RIV/68081766:_____/20:00523876 RIV/00216224:14310/20:00115848

Result on the web

<a href="https://actavet.vfu.cz/media/pdf/actavet_2020089010079.pdf" target="_blank" >https://actavet.vfu.cz/media/pdf/actavet_2020089010079.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2754/avb202089010079" target="_blank" >10.2754/avb202089010079</a>

Result language

angličtina

Original language name

Measurement of phagocyte activity in heterotherms

Original language description

The heterotherm immune system undergoes significant variation in response to life cycle periodicity and torpor. As heterothermic bats are important reservoirs of zoonotic agents and modulation of immune activity can affect host-pathogen interactions, this work aimed at developing a suitable method for assessing heterotherm phagocyte activity. Chemiluminescence measurements were evaluated by mathematical and mechanistic approaches, both of which yielded comparable results in time-related parameters of phagocyte activity. Using a mathematical method, however, we developed a model that can be applied to particular specimens. The proposed equation offers a simple and reliable tool for comparing phagocyte activity, the values of which can be used for further analysis. While time-related parameters of bat phagocyte activity varied with measurement temperature, with the onset of respiratory burst at 38 degrees C being quicker than at 25 degrees C, quantitative values of phagocyte activity were not influenced by measurement temperature. Further, homeotherm phagocyte activity parameters were more variable at 25 degrees C. Considering there was no influence of measurement temperature on the total volume of heterotherm phagocyte activity, we suggest that parameters measured at 25 degrees C are more representative of the immune status adapted to physiological extremes at low body temperatures.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40301 - Veterinary science

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta veterinaria Brno

ISSN

0001-7213

e-ISSN

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Volume of the periodical

89

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

9

Pages from-to

79-87

UT code for WoS article

000529064300010

EID of the result in the Scopus database

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