First report of colistin resistance gene mcr-1 from wildlife in Russia

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F20%3A43878773" target="_blank" >RIV/62157124:16270/20:43878773 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16810/20:43878773
Result on the web
<a href="https://fvhe.vfu.cz/files/upload/media-verejnost/sborniky-z-konferenci/KMVP%202020_sborn%C3%ADk.pdf" target="_blank" >https://fvhe.vfu.cz/files/upload/media-verejnost/sborniky-z-konferenci/KMVP%202020_sborn%C3%ADk.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
First report of colistin resistance gene mcr-1 from wildlife in Russia
Original language description
The aim of this study was to isolate and characterize Enterobacterales isolates with reduced susceptibility to colistin from Red and Black Kites (Milvus milvus and Milvus migrans, respectively) and to assess their potential risk as vectors and reservoirs of colistin resistance genes. Isolates (6%, n=168) that showed reduced susceptibility to colistin (3.5mg/L) were identified using MALDI-TOF MS and tested for mobile colistin resistance genes (mcr-1-mcr-8) by PCR. One mcr-1-positive E. coli isolate carried mcr-1 gene and was resistant to colistin (MIC > 4 mg/L) and susceptible to 18 antibiotics by broth dilution and disk diffusion methods, respectively. WGS using MiSeq (Illumina) revealed the mcr-1-positive E. coli sample belonged to ST2280. The mcr-1 gene was located on conjugative IncI2 plasmid pDR164 (59891 bp, GenBank number MK542639). In this study we present the first report of mcr-1 positive E. coli isolate from wildlife in Russia
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Sborník příspěvků XXII. konference mladých vědeckých pracovníků s mezinárodní účastí
ISBN
978-80-7305-846-3
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
109-111
Publisher name
Veterinární a farmaceutická univerzita Brno
Place of publication
Brno
Event location
Brno
Event date
May 20, 2020
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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