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Effect of Cephalosporin Antibiotics on the Activity of Yoghurt Cultures

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F22%3A43880422" target="_blank" >RIV/62157124:16270/22:43880422 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.mdpi.com/2304-8158/11/18/2751" target="_blank" >https://www.mdpi.com/2304-8158/11/18/2751</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/foods11182751" target="_blank" >10.3390/foods11182751</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Effect of Cephalosporin Antibiotics on the Activity of Yoghurt Cultures

  • Original language description

    The presence of antibiotics in milk is a significant problem affecting technological safety of dairy products. The aim of the study was to determine the sensitivity of yoghurt cultures to residual levels of selected cephalosporin antibiotics (cephalexin, cefoperazone, cefquinome, cefazolin, ceftiofur). Five yoghurt cultures were selected containing strains of Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus. Artificially fortified milk samples (whole pasteurised milk, 85 °C, 3-5 s) with cephalosporins at a concentration of maximum residue limit were used to evaluate the sensitivity of the yoghurt cultures by monitoring pH, titratable acidity and the concentration of selected organic acids (lactic, pyruvic, citric, acetic, orotic, oxalic, formic, uric and succinic acids) at the end of fermentation (43 °C, 4-5.5 h, pH &lt;= 4.6). Titratable acidity was determined by the Soxhlet-Henkel method and organic acid concentration was monitored by reversed-phase HPLC. Ceftiofur had the greatest effect on yoghurt culture activity, with a statistically highly significant effect (p &lt; 0.05) on pH, titratable acidity and the contents of lactic, pyruvic and acetic acids in all cultures. Other cephalosporins also showed an inhibitory effect on yoghurt metabolism as seen by the evaluation of lactic and pyruvic acid concentrations.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    40301 - Veterinary science

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Foods

  • ISSN

    2304-8158

  • e-ISSN

    2304-8158

  • Volume of the periodical

    11

  • Issue of the periodical within the volume

    18

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    17

  • Pages from-to

    nestrankovano

  • UT code for WoS article

    000858324300001

  • EID of the result in the Scopus database