Efficacy of Newly Synthesized, 44Bu Ultrashort-Acting, Beta-Adrenergic Antagonist to Isoprenaline-Induced Tachycardia - Comparison With Esmolol

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F04%3A00000298" target="_blank" >RIV/62157124:16370/04:00000298 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16170/04:00000223 RIV/00216224:14110/04:00030817
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Efficacy of Newly Synthesized, 44Bu Ultrashort-Acting, Beta-Adrenergic Antagonist to Isoprenaline-Induced Tachycardia - Comparison With Esmolol
Original language description
The aim of this study was in vivo testing of the action of a newly synthesized potential ultrashort acting beta-blocker on the heart rate in the laboratory rat. Doses at concentrations of 1.5mg#kg-1,2.5mg#kg-1and 3.5mg#kg-1 of body mass were tested. Bradycardiac effect of the compound 44Bu was compared with the action of esmolol under the same experimental conditions.
Czech name
Efficacy of Newly Synthesized, 44Bu Ultrashort-Acting, Beta-Adrenergic Antagonist to Isoprenaline-Induced Tachycardia - Comparison With Esmolol
Czech description
Efficacy of Newly Synthesized, 44Bu Ultrashort-Acting, Beta-Adrenergic Antagonist to Isoprenaline-Induced Tachycardia - Comparison With Esmolol

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Project
<a href="/en/project/NL7455" target="_blank" >NL7455: Monitoring of the Dependence of Effect on Dose and of Basic Pharmacokinetic Parameters in Original Substances with Antioxidative Effect</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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