Oxycellulose as mucoadhesive polymer in buccal tablets
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F10%3A00002628" target="_blank" >RIV/62157124:16370/10:00002628 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Oxycellulose as mucoadhesive polymer in buccal tablets
Original language description
The objective of this article was the formulation of buccal mucoadhesive tablets, based on oxidized cellulose (OC), in this term new pharmaceutical excipient, and evaluation of OC influence on physico-chemical properties of prepared tablets and their dissolution profiles. Besides usual excipients and mucoadhesive polymers, formulations contained 5 mg of model drug - cetylpyridinium chloride (CPC). The aim of this experiment was to ensure 8 hours prolonged release of CPC and its salivary concentration higher than its MIC (5 ?g/ml), without the necessity of residual tablet fragments elimination from oral cavity.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/2A-1TP1%2F073" target="_blank" >2A-1TP1/073: *New pharmaceutical products based on polysaccharides</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Drug Development and Industrial Pharmacy
ISSN
0363-9045
e-ISSN
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Volume of the periodical
36
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
16
Pages from-to
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UT code for WoS article
000282143700012
EID of the result in the Scopus database
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