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Oxycellulose as mucoadhesive polymer in buccal tablets

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F10%3A00002628" target="_blank" >RIV/62157124:16370/10:00002628 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Oxycellulose as mucoadhesive polymer in buccal tablets

  • Original language description

    The objective of this article was the formulation of buccal mucoadhesive tablets, based on oxidized cellulose (OC), in this term new pharmaceutical excipient, and evaluation of OC influence on physico-chemical properties of prepared tablets and their dissolution profiles. Besides usual excipients and mucoadhesive polymers, formulations contained 5 mg of model drug - cetylpyridinium chloride (CPC). The aim of this experiment was to ensure 8 hours prolonged release of CPC and its salivary concentration higher than its MIC (5 ?g/ml), without the necessity of residual tablet fragments elimination from oral cavity.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FR - Pharmacology and apothecary chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/2A-1TP1%2F073" target="_blank" >2A-1TP1/073: *New pharmaceutical products based on polysaccharides</a><br>

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Drug Development and Industrial Pharmacy

  • ISSN

    0363-9045

  • e-ISSN

  • Volume of the periodical

    36

  • Issue of the periodical within the volume

    9

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    16

  • Pages from-to

  • UT code for WoS article

    000282143700012

  • EID of the result in the Scopus database