The Development of Eudragit(R) NM-Based Controlled Release Matrix Tablets

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F12%3A43871088" target="_blank" >RIV/62157124:16370/12:43871088 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

The Development of Eudragit(R) NM-Based Controlled Release Matrix Tablets

Original language description

Eudragit(R)NM, was investigated as the matrix former in combination with microcrystalline cellulose as an insoluble filler for preparing controlled-release tablets containing model drugs with different solubility. A desirable release profile (at pH 6.8)was achieved only for freely soluble drugs when the ratio of drug/insoluble filler was 1:1 and polymer concentration ranged in interval 11.3-13.8% in tablets. Presented composition of matrix systems was not suitable for the incorporation of poorly soluble drugs

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

—

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Medicina-Lithuania

ISSN

1010-660X

e-ISSN

—

Volume of the periodical

48

Issue of the periodical within the volume

4

Country of publishing house

LT - LITHUANIA

Number of pages

11

Pages from-to

192-202

UT code for WoS article

000309628200004

EID of the result in the Scopus database

—