Azone Analogues: Classification, Design, and Transdermal Penetration Principles
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F12%3A43871548" target="_blank" >RIV/62157124:16370/12:43871548 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/med.20227" target="_blank" >http://dx.doi.org/10.1002/med.20227</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/med.20227" target="_blank" >10.1002/med.20227</a>
Alternative languages
Result language
angličtina
Original language name
Azone Analogues: Classification, Design, and Transdermal Penetration Principles
Original language description
The development in the field of pharmaceutical dosage forms results in the discovery of additional highly sophisticated drug delivery systems that allow maintaining a constant level of the active substance in an organism. Transdermal therapeutic systemsare an excellent alternative to conventional pharmaceutical dosage forms. However, the application of transdermal drug delivery faces the problem of insufficient or no penetration of active pharmaceutical substances through the skin. This review articledescribes the possible fundamental mechanisms of penetration through the skin barrier and refers to the classification of skin penetration enhancers. Azone-like enhancers are considered in detail and classified according to their structure on the basis of medicinal chemistry approaches. The article also provides a review of original transdermal penetration enhancers prepared in our laboratory and discusses the relationship between the chemical structure of the described Azone analogues a
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Medicinal research reviews
ISSN
0198-6325
e-ISSN
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Volume of the periodical
32
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
41
Pages from-to
907-947
UT code for WoS article
000307384100001
EID of the result in the Scopus database
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